Climate change-induced extreme weather suppresses salicylic acid (SA) production in plants, compromising immunity. This study reveals that high temperatures (28°C) reduce the formation of GUANYLATE BINDING PROTEIN-LIKE 3 (GBPL3) defense-activated biomolecular condensates (GDACs), impairing recruitment of GBPL3 and SA-associated mediators to promoters of *CBP60g* and *SARD1*, master immune transcription factors. Optimizing *CBP60g* expression broadened metabolic responses to elevated temperatures, suggesting a strategy for enhancing climate-resilient plant immunity.

Jong Hum Kim, Christian Denv. Castroverde, Shuai Huang, Chao Li, Richard Hilleary, Adam Seroka, Reza Sohrabi, Diana Medina-Yerena, Bethany Huot, Jie Wang, Kinya Nomura, Shoron K. Marr, Mary C. Wildermuth, Tao Chen, John D. MacMicking, Sheng Yang He