This study presents the development of a mass-transduction-based MXene gas sensor using MXenes as the receptor and micro-quartz tuning fork (MQTF) as the transducer. The sensor's operation relies on the mass change induced by gas analyte interaction with MXenes, resulting in a resonant frequency shift of the MQTF. This approach eliminates the reliance on MXene conductivity, allowing for broader chemical modification without performance compromise. Surface engineering of Ti3C2Tx MXenes achieved high sensitivity and tunable selectivity for CO, SO2, and NH3 detection. The sensor demonstrated exceptional performance, customizable selectivity, and cost-effectiveness, showing promise for applications in air quality monitoring, wearable devices, IoT, and robotics.