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High Prevalence of Respiratory Co-Infections and Risk Factors in COVID-19 Patients at Hospital Admission During an Epidemic Peak in China

Medicine and Health

High Prevalence of Respiratory Co-Infections and Risk Factors in COVID-19 Patients at Hospital Admission During an Epidemic Peak in China

X. Zhu, F. Tian, et al.

This intriguing study evaluated 716 COVID-19 patients in a Chinese hospital, revealing a staggering 76.82% co-infection rate with 11 pathogens, predominantly bacterial. The most common culprits were *Streptococcus pneumoniae* and *Haemophilus influenzae*. With insights on mortality risk factors such as dyspnea and *Mycoplasma pneumoniae* co-infection, researchers stress the importance of better antibiotic management. This vital work was conducted by Xiaoying Zhu, Fengqin Tian, Yulei Li, Qunfeng Lu, Qinqin Long, Xidai Long, and Demin Cao.

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Playback language: English
Abstract
This retrospective study analyzed 716 COVID-19 patients admitted to a Chinese hospital. 76.82% showed co-infection with 11 pathogens; bacterial co-infections (74%) were most common, primarily *Streptococcus pneumoniae* and *Haemophilus influenzae*. Viral co-infections (15%) involved influenza A and respiratory syncytial virus. Risk factors for mortality included dyspnea, hypoproteinemia, low lymphocyte counts, and *Mycoplasma pneumoniae* co-infection. The study highlights the high prevalence of co-infections and suggests a need for improved antibiotic stewardship.
Publisher
Infection and Drug Resistance
Published On
Oct 25, 2023
Authors
Xiaoying Zhu, Fengqin Tian, Yulei Li, Qunfeng Lu, Qinqin Long, Xidai Long, Demin Cao
Tags
COVID-19
co-infection
bacterial pathogens
mortality risk factors
antibiotic stewardship
Streptococcus pneumoniae
Mycoplasma pneumoniae

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