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Functionalizing tandem mass tags for streamlining click-based quantitative chemoproteomics

Biology

Functionalizing tandem mass tags for streamlining click-based quantitative chemoproteomics

N. R. Burton and K. M. Backus

Explore the innovative silane-based cleavable linkers for isotopically-labeled proteomics-tandem mass tag (sCIP-TMT) platform, developed by Nikolas R. Burton and Keriann M. Backus. This cutting-edge technology enables efficient sample preparation, achieving high throughput and coverage while accurately quantifying results in chemoproteomic applications. Unlock the potential of identifying covalent interactions with a remarkable capacity for detecting liganded cysteines.

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