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Abstract
This study investigated the prognostic value of superior temporal sulcus (STS) depth asymmetry in healthy fetuses for later language abilities, language localization, and language-related white matter tracts. Less right lateralization of the fetal STS depth was significantly associated with better verbal abilities, with fetal STS depth asymmetry explaining more than 40% of variance in verbal skills 6–13 years later. Less right fetal STS depth asymmetry correlated with increased left language localization during childhood. The findings suggest fetal STS asymmetry may be a diagnostic biomarker of language development.
Publisher
Communications Biology
Published On
Jan 27, 2023
Authors
Lisa Bartha-Doering, Kathrin Kollndorfer, Ernst Schwartz, Florian Ph.S. Fischmeister, Georg Lang, Michael Weber, Sonja Lackner-Schmelz, Patric Kienast, Marlene Stümpflen, Athena Taymourtash, Sophie Mandl, Johanna Alexopoulos, Daniela Prayer, Rainer Seidl, Gregor Kasprian
Tags
fetal development
language abilities
superior temporal sulcus
STS depth asymmetry
language localization
diagnostic biomarker
child development
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