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Entrectinib in ROS1-positive advanced non-small cell lung cancer: the phase 2/3 BFAST trial

Medicine and Health

Entrectinib in ROS1-positive advanced non-small cell lung cancer: the phase 2/3 BFAST trial

S. Peters, S. M. Gadgeel, et al.

This phase 2/3 BFAST trial demonstrated that entrectinib provides a remarkable confirmed objective response rate of 81.5% in treatment-naive patients with ROS1-positive NSCLC identified through liquid biopsies. Backed by the authors, these results advocate for the crucial role of liquid biopsies in clinical decision-making for advanced NSCLC.

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