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Enhancing detection accuracy via controlled release of 3D-printed microlattice nasopharyngeal swabs

Medicine and Health

Enhancing detection accuracy via controlled release of 3D-printed microlattice nasopharyngeal swabs

R. Xiao, J. Li, et al.

Discover groundbreaking advancements in clinical diagnostics through the innovative 3D-printed open-cell microlattice nasopharyngeal swabs developed by Ran Xiao and team. These swabs not only enhance flexibility and release concentration but also achieve an impressive ~100% recovery efficiency, promising significantly improved antibody detection sensitivity and accuracy.

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Playback language: English
Abstract
Nasopharyngeal (NP) swabs are crucial for clinical specimen detection, but commercial swabs often dilute samples, reducing accuracy. This study introduces 3D-printed open-cell microlattice NP swabs with a controlled release (CR) mechanism. These swabs exhibit significantly higher flexibility, larger and customizable release volume, and drastically increased release concentration compared to traditional swabs. The high recovery efficiency (~100%) and ability to quantify analyte levels improve antibody detection sensitivity and accuracy, showcasing the potential for enhanced clinical diagnostics and broader biomedical device design.
Publisher
Communications Engineering
Published On
Mar 04, 2024
Authors
Ran Xiao, Jiaheng Li, Yue Fung Wong, Lok Ting Chu, Yingxin Zhu, Liqiang Wang, Minghui Wu, Dingkun Zhang, Meng Gong, Joseph Lai, Kannie W. Y. Chan, Rong Fan, Ting-Hsuan Chen, Yang Lu
Tags
nasopharyngeal swabs
3D-printed
microlattice
controlled release
clinical diagnostics

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