Veterinary Science

Enhanced risk of cancer in companion animals as a response to the longevity

M. Tanaka, S. Yamaguchi, et al.

This groundbreaking study by Moeko Tanaka, Sachi Yamaguchi, and Yoh Iwasa delves into the surprising connection between increased longevity in companion animals and elevated cancer risks. Through a multi-step cancer model, it reveals how environmental advancements may heighten cancer prevalence initially, while evolutionary responses might eventually reduce genomic error rates. Discover the intricate dynamics between short-term challenges and long-term adaptations in the face of changing environments!

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Abstract

This study investigates the enhanced cancer risk in companion animals due to increased longevity. Using a multi-step cancer model, the authors show that environmental improvements leading to longer lifespans increase cancer prevalence in the short term, even without changes in genomic error rates. However, in the long term, evolution favors lower genomic error rates, mitigating cancer risk. The model explores the interplay between short-term (non-evolutionary) and long-term (evolutionary) responses to environmental changes.

Publisher

Scientific Reports

Published On

Nov 11, 2020

Authors

Moeko Tanaka, Sachi Yamaguchi, Yoh Iwasa

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