BiologyNature Communications
Engineering intelligent chassis cells via recombinase-based MEMORY circuits
B. D. Huang, D. Kim, et al.
This groundbreaking research by Brian D. Huang, Dowan Kim, Yongjoon Yu, and Corey J. Wilson successfully engineers intelligent *Escherichia coli* strains that utilize an advanced system of genome-integrated recombinases. These innovative MEMORY chassis cells allow for programmable gain or loss of functions, enabling communication and memory capabilities in probiotic strains, paving the way for advanced living therapeutics.
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