Medicine and Health

Endogenous theta stimulation during meditation predicts reduced opioid dosing following treatment with Mindfulness-Oriented Recovery Enhancement

J. Hudak, A. W. Hanley, et al.

This groundbreaking study conducted by Justin Hudak, Adam W Hanley, William R Marchand, Yoshio Nakamura, Brandon Yabko, and Eric L Garland reveals how Mindfulness-Oriented Recovery Enhancement (MORE) can significantly lower opioid usage in veterans with chronic pain, while also boosting brain activity associated with self-control. Discover the powerful intersection of mindfulness and neuroscience!

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Abstract

This study investigated the effects of Mindfulness-Oriented Recovery Enhancement (MORE), a mindfulness-based intervention, on opioid dosing in veterans with chronic pain. EEG data were collected during meditation sessions before and after an 8-week MORE program or a supportive psychotherapy control. The MORE group showed increased alpha and theta power, particularly theta, and increased frontal midline theta coherence. Importantly, MORE significantly reduced opioid dosage, an effect partially mediated by increased frontal theta power. These findings suggest that mindfulness meditation may stimulate endogenous theta activity in the prefrontal cortex, enhancing inhibitory control over opioid use.

Publisher

Neuropsychopharmacology

Published On

Authors

Justin Hudak, Adam W Hanley, William R Marchand, Yoshio Nakamura, Brandon Yabko, Eric L Garland

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