Medicine and Health

Effects of vitamin D supplementation on cardiometabolic parameters among patients with metabolic syndrome: A systematic review and GRADE evidence synthesis of randomized controlled trials

S. Aquino, A. Cunha, et al.

Discover the intriguing findings of a systematic review focused on the impact of vitamin D supplementation on cardiometabolic parameters in adults with metabolic syndrome. Conducted by a team of researchers from the Federal University of Rio Grande do Norte, this study reveals significant insights into the effectiveness of vitamin D in managing metabolic health.

00:00

Playback language: English

Index

Abstract

This systematic review and GRADE evidence synthesis investigated the effectiveness of vitamin D supplementation (VDS) in controlling cardiometabolic parameters among adults with metabolic syndrome (MetS). Seven randomized controlled trials (RCTs) were included, revealing high heterogeneity. While all studies showed increased serum 25(OH)D levels in intervention groups, only two demonstrated significant decreases in triglyceride levels and waist circumference. However, the certainty of evidence was very low for triglycerides and low for waist circumference, with moderate certainty for fasting glucose, blood pressure, and HDL-c. The evidence does not support VDS for reducing triglyceride levels and waist circumference in adults with MetS.

Publisher

Heliyon

Published On

Oct 12, 2023

Authors

Séphora Aquino, Aline Cunha, Josivan Gomes Lima, Karine Sena-Evangelista, Antonio Gouveia Oliveira, Ricardo Ney Cobucci, Lucia Fc Pedrosa

Related Publications

Explore these studies to deepen your understanding of the subject.

Medicine and Health

Taurine reduces the risk for metabolic syndrome: a systematic review and meta-analysis of randomized controlled trials

C. Tzang, L. Chi, et al.

Medicine and Health

The effects of omega 3 fatty acids on the serum concentrations of pro inflammatory cytokines and depression status in patients with bipolar disorder: A randomized double-blind controlled clinical trial

H. Eslahi, M. Shakiba, et al.

Medicine and Health

Effects of vitamin D in pregnancy on maternal and offspring health-related outcomes: An umbrella review of systematic review and meta-analyses

M. Chien, C. Huang, et al.

Medicine and Health

Nutritional and Exercise-Focused Lifestyle Interventions and Glycemic Control in Women with Diabetes in Pregnancy: A Systematic Review and Meta-Analysis of Randomized Clinical Trials

C. F. Dingena, D. Arofikina, et al.

Listen, Learn & Level Up

Over 10,000 hours of research content in 25+ fields, available in 12+ languages.

No more digging through PDFs, just hit play and absorb the world's latest research in your language, on your time.

listen to research audio papers with researchbunny