logo
ResearchBunny Logo
Effects of vitamin D in pregnancy on maternal and offspring health-related outcomes: An umbrella review of systematic review and meta-analyses

Medicine and Health

Effects of vitamin D in pregnancy on maternal and offspring health-related outcomes: An umbrella review of systematic review and meta-analyses

M. Chien, C. Huang, et al.

This comprehensive umbrella review reveals how vitamin D deficiency during pregnancy is linked to a host of risks including preterm birth and gestational diabetes, while supplementation showcases significant benefits for maternal and offspring health. The research, conducted by Mei-Chun Chien, Chueh-Yi Huang, Jie-Huei Wang, Chia-Lung Shih, and Pensee Wu, emphasizes the critical need for monitoring vitamin D status during this crucial period.

00:00
00:00
Playback language: English
Abstract
This umbrella review summarizes systematic reviews and meta-analyses evaluating the effects of vitamin D deficiency and supplementation during pregnancy on maternal and offspring health. Vitamin D deficiency was associated with increased risks of preterm birth, small-for-gestational-age/low birth weight infants, recurrent miscarriage, bacterial vaginosis, and gestational diabetes mellitus (GDM). Supplementation increased birth weight and reduced risks of maternal pre-eclampsia, miscarriage, vitamin D deficiency, fetal/neonatal mortality, childhood attention-deficit hyperactivity disorder, and autism spectrum disorder. In women with GDM, supplementation reduced risks of maternal hyperbilirubinemia, polyhydramnios, macrosomia, fetal distress, and neonatal hospitalization. Monitoring vitamin D status and supplementation of >400 IU/day are recommended.
Publisher
Nutrition and Diabetes
Published On
May 30, 2024
Authors
Mei-Chun Chien, Chueh-Yi Huang, Jie-Huei Wang, Chia-Lung Shih, Pensee Wu
Tags
vitamin D deficiency
pregnancy
maternal health
supplementation
offspring health
gestational diabetes
preterm birth
Listen, Learn & Level Up
Over 10,000 hours of research content in 25+ fields, available in 12+ languages.
No more digging through PDFs, just hit play and absorb the world's latest research in your language, on your time.
listen to research audio papers with researchbunny