This study presents a novel nanopesticide formulation using tebuconazole encapsulated in temperature-responsive copolymers. The flash nanoprecipitation method yielded leaf-adhesive, water-dispersed nanopesticides with improved deposition and reduced wash-off compared to commercial formulations. The nanopesticide demonstrated enhanced wettability and a 40° reduction in contact angle on foliage. Furthermore, it showed significantly reduced acute toxicity to zebrafish.