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De novo generation of multi-target compounds using deep generative chemistry

Medicine and Health

De novo generation of multi-target compounds using deep generative chemistry

B. P. Munson, M. Chen, et al.

Discover how POLYGON, developed by Brenton P. Munson and colleagues, harnesses generative reinforcement learning to design polypharmacology drugs that inhibit multiple protein targets. With impressive results in synthesizing compounds, this innovative approach holds promise for the future of drug design.

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