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Comparison of hydroxyapatite and fluoride oral care gels for remineralization of initial caries: a pH-cycling study

Medicine and Health

Comparison of hydroxyapatite and fluoride oral care gels for remineralization of initial caries: a pH-cycling study

B. T. Amaechi, P. A. Abdulazees, et al.

Discover the fascinating findings of a groundbreaking study where researchers evaluated the effectiveness of a hydroxyapatite-based gel versus a high-fluoride gel in remineralizing initial caries lesions. Conducted by Bennett T. Amaechi and team, the results revealed that both gels significantly outperformed artificial saliva, with the hydroxyapatite gel showing uniform remineralization across lesions.

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Playback language: English
Abstract
This *in vitro* study compared the remineralization efficacy of a hydroxyapatite-based gel (15% HAP) applied daily and a high-fluoride (12,500 ppm F) gel applied weekly on initial caries lesions, using artificial saliva as a control. Both gels showed significant remineralization (*p* < 0.0001), with no significant difference between them. Both gels were significantly more effective than artificial saliva alone (*p* < 0.001). The hydroxyapatite gel demonstrated homogenous remineralization across the lesion, while the fluoride gel's effect was limited to the surface zone. The study concludes that 15% HAP gel is as effective as the high-fluoride gel in remineralizing initial caries lesions.
Publisher
BDJ Open
Published On
Jul 22, 2020
Authors
Bennett T. Amaechi, Parveez Ahamed AbdulAzees, Linda O. Okoye, Frederic Meyer, Joachim Enax
Tags
remineralization
caries lesions
hydroxyapatite gel
high-fluoride gel
in vitro study
oral health

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