This paper introduces a novel barbed arrow-like structure membrane (BAS Mem) for lateral-flow assays (LFAs) of cardiac troponin I (cTnI), a key biomarker for acute myocardial infarction (AMI). The BAS Mem's unique structure enables unidirectional, fast liquid flow with an unprecedented rectification coefficient of 14.5. LFAs using BAS Mem achieve cTnI detection within 240 seconds, with a limit of detection of 1.97 ng mL⁻¹ and high sensitivity (93.3%) and specificity (100%) in clinical samples. This ultra-fast and highly sensitive assay shows great promise for timely AMI diagnosis.
