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Abstract
This study investigated the relationship between plasma phospholipid cis-vaccenic acid (cVA) and insulin resistance markers in hyperlipidemic men. 231 men with newly diagnosed hyperlipidemia were analyzed, stratified into upper (Q4) and lower (Q1) quartiles based on cVA content. Q4 showed lower plasma insulin, HOMA-IR, and apolipoprotein B, but higher non-esterified fatty acids (NEFA). The Q4 group also had lower n-6 polyunsaturated fatty acids and higher monounsaturated fatty acids. These findings suggest a positive association between plasma PL cVA and insulin sensitivity in hyperlipidemic men.
Publisher
Nutrition and Diabetes
Published On
Sep 11, 2024
Authors
Jaroslav Macášek, Barbora Staňková, Aleš Žák, Markéta Růžičková, Radan Brüha, Simona Kutová, Marek Vecka, Miroslav Zeman
Tags
cis-vaccenic acid
insulin resistance
hyperlipidemia
lipid profile
metabolic health
plasma phospholipids
fatty acids

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