PsychologyeLife
Altered hierarchical auditory predictive processing after lesions to the orbitofrontal cortex
O. Asko, A. O. Blenkmann, et al.
This study, conducted by the authors listed in <Authors>, probes how lesions to the orbitofrontal cortex (OFC) alter hierarchical predictive processing in audition. Using a local–global tone paradigm, OFC patients showed attenuated MMN and altered P3a responses to prediction violations while P3b to global-rule breaches remained preserved—revealing level-specific impacts of OFC damage.
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