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Accelerometer-based sedentary time and physical activity with MASLD and liver cirrhosis in 2684 British adolescents

Medicine and Health

Accelerometer-based sedentary time and physical activity with MASLD and liver cirrhosis in 2684 British adolescents

A. O. Agbaje

This study conducted by Andrew O. Agbaje and colleagues explores how sedentary time, light physical activity, and moderate-to-vigorous physical activity during childhood relate to liver health in adolescents. The findings indicate that increasing activity levels can significantly reduce the risk of serious liver conditions like cirrhosis and steatosis.

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Playback language: English
Abstract
This study examined the associations of cumulative sedentary time (ST), light physical activity (LPA), and moderate-to-vigorous PA (MVPA) from childhood with longitudinal changes in liver indices and enzymes in 2684 British adolescents. Increased ST was associated with higher odds of liver cirrhosis and severe liver steatosis, while increased LPA and MVPA were associated with lower odds of these conditions. MVPA's effect on lowering liver steatosis was suppressed by increased fat mass. Increasing LPA, sustaining MVPA, and decreasing ST from childhood may attenuate the risk of severe liver steatosis and liver cirrhosis.
Publisher
npj Gut and Liver
Published On
May 29, 2024
Authors
Andrew O. Agbaje
Tags
sedentary time
light physical activity
moderate-to-vigorous physical activity
liver health
adolescents

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