This study examined the associations of cumulative sedentary time (ST), light physical activity (LPA), and moderate-to-vigorous PA (MVPA) from childhood with longitudinal changes in liver indices and enzymes in 2684 British adolescents. Increased ST was associated with higher odds of liver cirrhosis and severe liver steatosis, while increased LPA and MVPA were associated with lower odds of these conditions. MVPA's effect on lowering liver steatosis was suppressed by increased fat mass. Increasing LPA, sustaining MVPA, and decreasing ST from childhood may attenuate the risk of severe liver steatosis and liver cirrhosis.
Publisher
npj Gut and Liver
Published On
May 29, 2024
Authors
Andrew O. Agbaje
Tags
sedentary time
light physical activity
moderate-to-vigorous physical activity
liver health
adolescents
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