This study investigated sex differences in glucose metabolism after a balanced mixed meal normalized to individual daily energy expenditure in 36 healthy young volunteers (18 men, 18 women). Fasting glucose was lower in women, but fasting insulin and C-peptide were similar. Linear mixed models showed no significant sex effect or sex-time interaction on postprandial glucose, insulin, or C-peptide. Area under the curve analysis revealed similar glycemic, insulinemic, and C-peptide responses between sexes. The study concludes that there is no sexual dimorphism in carbohydrate metabolism regulation in young adults when consuming a meal normalized to individual energy expenditure.
Publisher
Nutrition and Diabetes
Published On
Feb 02, 2022
Authors
Alessandro Leone, Ramona De Amicis, Simona Bertoli, Angela Spadafranca, Giulia De Carlo, Alberto Battezzati
Tags
glucose metabolism
sex differences
postprandial responses
healthy young adults
insulin
carbohydrate metabolism
energy expenditure
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