Biology

A versatile and customizable low-cost 3D-printed open standard for microscopic imaging

B. Diederich, R. Lachmann, et al.

Explore the innovative UC2—a low-cost, 3D-printed, open-source modular microscopy toolbox developed by a team of researchers, including Benedict Diederich and René Lachmann. This versatile suite includes designs for monitoring cell differentiation and performing volumetric observations, pushing the boundaries of optical science.

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Abstract

Modern biological imaging microscopes are often expensive black boxes. UC2 (You. See. Too.) is a low-cost, 3D-printed, open-source, modular microscopy toolbox. The authors demonstrate its versatility by building a brightfield microscope monitoring cell differentiation and a light sheet fluorescence microscope for volumetric observations. The design aims to establish an open standard in optics, facilitating interfacing with various platforms and promoting easy replication and modification.

Publisher

Nature Communications

Published On

Nov 25, 2020

Authors

Benedict Diederich, René Lachmann, Swen Carlstedt, Barbora Marsikova, Haoran Wang, Xavier Uwurukundo, Alexander S. Mosig, Rainer Heintzmann

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