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A randomized, double-blind, active placebo-controlled study of efficacy, safety, and durability of repeated vs single subanesthetic ketamine for treatment-resistant depression

Medicine and Health

A randomized, double-blind, active placebo-controlled study of efficacy, safety, and durability of repeated vs single subanesthetic ketamine for treatment-resistant depression

P. R. Shiroma, P. Thuras, et al.

This groundbreaking study by Paulo R. Shiroma and colleagues investigates the efficacy and safety of repeated versus single subanesthetic ketamine infusions for treatment-resistant depression. While no significant difference was observed in primary outcomes, the results hint at potential benefits of repeated ketamine infusions, paving the way for further research to optimize treatment.

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