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Abstract
This work reports the development of a new microchannel capillary flow assay (MCFA) platform for chemiluminescence-based ELISA using lyophilized reagents. The MCFA platform, utilizing passive flow control and a smartphone-based optical detector connected via USB-OTG, achieves a limit of detection (LOD) of 8 ng/mL for PfHRP2, a malaria biomarker. The system is cost-effective, portable, and easily adaptable for other biomarkers.
Publisher
Microsystems & Nanoengineering
Published On
Jan 01, 2020
Authors
Sthitodhi Ghosh, Kashish Aggarwal, Vinitha T. U, Thinh Nguyen, Jungyoup Han, Chong H. Ahn
Tags
microchannel
capillary flow
chemiluminescence
ELISA
PfHRP2
biomarkers
smartphone detection

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