Biology

A genetically encoded BRET-based SARS-CoV-2 Mpro protease activity sensor

A. M. Geethakumari, W. S. Ahmed, et al.

Discover groundbreaking insights into SARS-CoV-2's main protease (Mpro) with innovative BRET-based sensors developed by Anupriya M. Geethakumari, Wesam S. Ahmed, Saad Rasool, Asma Fatima, S. M. Nasir Uddin, Mustapha Aouida, and Kabir H. Biswas. These sensors allow for real-time detection of Mpro activity, offering valuable tools for drug discovery and functional genomics in the battle against COVID-19.

00:00

Playback language: English

Related Publications

Explore these studies to deepen your understanding of the subject.

Medicine and Health

Multivalent nanoparticle-based vaccines protect hamsters against SARS-CoV-2 after a single immunization

S. Chiba, S. J. Frey, et al.

Medicine and Health

A CRISPR-based ultrasensitive assay detects attomolar concentrations of SARS-CoV-2 antibodies in clinical samples

Y. Tang, T. Song, et al.

Medicine and Health

A small molecule compound with an indole moiety inhibits the main protease of SARS-CoV-2 and blocks virus replication

S. Hattori, N. Higashi-kuwata, et al.

Chemistry

A sustainable synthesis of the SARS-CoV-2 Mpro inhibitor nirmatrelvir, the active ingredient in Paxlovid

J. R. A. Kincaid, J. C. Caravez, et al.

Listen, Learn & Level Up

Over 10,000 hours of research content in 25+ fields, available in 12+ languages.

No more digging through PDFs, just hit play and absorb the world's latest research in your language, on your time.

listen to research audio papers with researchbunny