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A dorsomedial prefrontal cortex-based dynamic functional connectivity model of rumination

Psychology

A dorsomedial prefrontal cortex-based dynamic functional connectivity model of rumination

J. Kim, J. R. Andrews-hanna, et al.

Rumination — repetitive negative thinking linked to depression — shows a distinct neural signature in the dorsomedial prefrontal cortex through dynamic resting-state connectivity. Using predictive modeling across five diverse samples (total n = 288), the authors identify a generalizable dmPFC-based marker that, when refined, predicts depression severity in adults with major depressive disorder. Research conducted by Jungwoo Kim, Jessica R. Andrews-Hanna, Hedwig Eisenbarth, Byeol Kim Lux, Hong Ji Kim, Eunjin Lee, Martin A. Lindquist, Elizabeth A. Reynolds Losin, Tor D. Wager, and Choong-Wan Woo.... show more
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