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A deep learning approach for morphological feature extraction based on variational auto-encoder: an application to mandible shape

Biology

A deep learning approach for morphological feature extraction based on variational auto-encoder: an application to mandible shape

M. Tsutsumi, N. Saito, et al.

Explore the groundbreaking Morpho-VAE, a unique framework that employs deep learning for shape analysis in image data. This innovative tool, developed by Masato Tsutsumi, Nen Saito, Daisuke Koyabu, and Chikara Furusawa, excels at distinguishing morphological features among different classes, particularly in primate mandible images, showcasing its potential for biological discoveries.

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Playback language: English
Abstract
This paper introduces Morpho-VAE, a landmark-free deep learning framework for shape analysis using image data. Morpho-VAE, a modified variational autoencoder (VAE), combines unsupervised and supervised learning to extract morphological features distinguishing different labeled classes. Applied to primate mandible images, it effectively clustered samples by family, even without correlation to phylogenetic distance. It also demonstrated reconstruction of missing segments in incomplete images, making it a versatile tool for biological shape analysis.
Publisher
npj Systems Biology and Applications
Published On
Jul 06, 2023
Authors
Masato Tsutsumi, Nen Saito, Daisuke Koyabu, Chikara Furusawa
Tags
Morpho-VAE
deep learning
shape analysis
primate mandible
morphological features
unsupervised learning
image data
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