Chemistry

A 13-million turnover-number anionic Ir-catalyst for a selective industrial route to chiral nicotine

C. Yin, Y. Jiang, et al.

Discover groundbreaking advancements in asymmetric hydrogenation with our ultra-efficient anionic Ir-catalyst, achieving remarkable enantioselectivities and million turnover numbers. This breakthrough, detailed by authors Congcong Yin, Ya-Fei Jiang, Fanping Huang, Cong-Qiao Xu, Yingmin Pan, Shuang Gao, Gen-Qiang Chen, Xiaobing Ding, Shao-Tao Bai, Qiwei Lang, Jun Li, and Xumu Zhang, paves the way for industrial-scale production of enantiopure nicotine at an unprecedented scale!