Advancing New Mechanisms and Emerging Treatments in Metastatic Castration Resistant Prostate Cancer (mCRPC)

📖 About the Opportunity

This competitive grant program seeks to support independent medical education addressing new mechanisms in mCRPC, including EZH2 inhibition and its possible role in prostate cancer. It also aims to address the continued unmet need for novel therapies in mCRPC.

Opportunity Details

• Date Published: September 08, 2025
• Application Deadline: October 14, 2025
• Category:
  • Postgraduate
  • Masters
  • PhD
  • Contest
  • Fully Funded
  • Grants
  • Postdoctoral

Sponsor Organization

• Pfizer

🎁 Benefits

• Individual projects requesting between $75,000 - $250,000 will be considered.
• The estimated total available budget related to this RFP is $500,000.
• Award amounts include:
  • Direct costs
  • Institutional overhead costs (capped at 28% per Pfizer policy)
  • Indirect costs

✅ Eligibility Criteria

Geographic Scope/Location of Project

• Priority Regions: United States and Europe
• Proposals with global reach are encouraged.

Applicant Eligibility

• Applicant organizations must be based in the United States or Europe.
• Eligible entities include:
  • Medical, dental, nursing, allied health, and/or pharmacy professional schools
  • Healthcare institutions (large and small)
  • Professional organizations/medical societies
  • Medical education companies
  • Other entities with a mission related to healthcare professional education and/or healthcare improvement

Additional Requirements

• Only organizations are eligible to receive grants, not individuals or medical practice groups.
• Projects involving multiple departments or institutions must ensure all institutions have a relevant role, with the requesting organization playing a key role.
• The applicant must be the project/program lead or an authorized designee (e.g., grant coordinator).
• The project/program lead must be an employee or contractor of the requesting organization.
• The requesting organization must be legally able to receive award funding directly from Pfizer Inc.

Accreditation for Continuing Education

• For projects offering continuing education credit, the requesting organization must be accredited.

🌟 Primary Area of Interest

Projects considered for Pfizer support will focus on increasing healthcare professional awareness and understanding in the following areas:

• Differentiated mechanism of action (MOA) of emerging therapies, including EZH2 inhibition and its possible role in prostate cancer.
• EZH2 and other novel mechanisms of disease (MOD) and their role in prostate cancer progression.
• Investigational thesis on how concomitant EZH2 and AR inhibition may suppress prostate cancer while delaying or overcoming ARPi resistance.
• Continued unmet need for novel therapies in mCRPC.
• mCRPC therapies beyond chemotherapy.
• Ongoing clinical trials that may be an option for patients today.

Examples of Educational Formats

• On-agenda educational sessions during live conferences.
• Multi-company supported, stand-alone symposia.
• Expert interviews recorded at live conferences, conference coverage reviews.
• Online articles, newsletter articles, training courses, webinars.
• Social media posted and linked content.
• Videos, podcasts, infographics, animations.

Target Audience

• Oncologists, urologists, oncology nurses, nurse practitioners, physician assistants, pharmacists, and other healthcare professionals involved in the care and treatment of people with prostate cancer.

📝 Application Date and Process

Important Instructions

Applications submitted without following these instructions will not be accepted.

Steps to Apply

1. Visit www.cybergrants.com/pfizer/knowledge and sign in.
   • First-time users should click “Create your password.”
   • Ensure organization information is up-to-date (e.g., prior reporting requirements completed, tax ID number updated, etc.).
2. Click the “Start A New Knowledge Gap Application” button.

Requirements for Submission

• Complete all required sections of the online application.
• Upload the proposal (see Appendix) in the General RFP Submission field.
• In the application:
  • For the question “Competitive Grant?” select “Yes”.
  • Select the following Primary Area of Interest: Oncology - Genitourinary - KG.
  • Select the following Competitive Grant Program Name: 2025 ONC Global mCRPC New Mechanisms IME.

📅 Application Deadline

October 14, 2025

🔗 Application Portal

• View details of Advancing New Mechanisms and Emerging Treatments in mCRPC.
• Apply for Advancing New Mechanisms and Emerging Treatments in mCRPC.

• Individual projects requesting between $75,000 - $250,000 will be considered.
• The estimated total available budget related to this RFP is $500,000.
• Award amounts include direct costs, institutional overhead costs (capped at 28% per Pfizer policy), and indirect costs.