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Systems immunology of transcriptional responses to viral infection identifies conserved antiviral pathways across macaques and humans

Biology

Systems immunology of transcriptional responses to viral infection identifies conserved antiviral pathways across macaques and humans

K. Ratnasiri, H. Zheng, et al.

In a groundbreaking study, researchers including Kalani Ratnasiri and Shirit Einav have conducted the largest transcriptome analysis of viral diseases in humans and macaques. Their findings uncover conserved antiviral responses and reveal distinct host reactions to various viruses, paving the way for advancements in understanding and combating viral infections.

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~3 min • Beginner • English
Abstract
Publisher
Cell Reports
Published On
Feb 27, 2024
Authors
Kalani Ratnasiri, Hong Zheng, Jiaying Toh, Shirit Einav, Catherine A Blish, Purvesh Khatri, Zhiyuan Yao, Veronica Duran, Michele Donato, Mario Roederer, Megha Kamath, John-Paul M Todd, Matthew Gagne, Kathryn E Foulds, Joseph R Francica, Kizzmekia S Corbett, Daniel C Douek, Robert A Seder
Tags
transcriptome analysis
viral disease
antiviral responses
macaques
humans
myeloid cells
T cell responses

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