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Abstract
This study investigated the relationship between self-compassion, caudate functional connectivity during self-appraisal, and adolescent suicide ideation. 79 depressed youth and 36 healthy controls underwent fMRI while evaluating self-descriptive phrases. Self-compassion was associated with stronger left caudate connectivity with bilateral posterior superior temporal sulcus/temporoparietal junction, left middle temporal gyrus (MTG), and left middle occipital gyrus during positive versus negative self-appraisals. Stronger left caudate-left MTG connectivity explained the association between higher self-compassion and lower suicide ideation, even after controlling for other factors. Left caudate to MTG connectivity during positive self-referential processing may be a potential biomarker for suicide risk reduction interventions.
Publisher
Translational Psychiatry
Published On
Aug 20, 2024
Authors
Guannim Liu, Guijuan Hao, Natasha Das, Janani Rantunaga, Corey Schneider, Li Yang, Karina Quevedo
Tags
self-compassion
suicide ideation
adolescents
fMRI
caudate connectivity
self-appraisal
mental health
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