Engineering and Technology

Quantitative, high-sensitivity measurement of liquid analytes using a smartphone compass

M. Ferris and G. Zabow

Discover an innovative smartphone-based platform developed by Mark Ferris and Gary Zabow that uses a built-in magnetometer for precise analyte sensing. This groundbreaking system exploits the unique properties of magnetic-hydrogel composites for sensitive and quantitative detection of glucose and pH levels, pushing the boundaries of liquid-based measurements!

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Abstract

This paper presents a novel smartphone-based analyte sensing platform utilizing the built-in magnetometer for signal transduction via analyte-responsive magnetic-hydrogel composites. The hydrogels dilate in response to targeted stimuli, displacing attached magnetic material, and a bilayer hydrogel amplifies this motion for sensitive, optics-free, quantitative liquid-based measurements. The concept is demonstrated with glucose-specific and pH-responsive hydrogels, achieving glucose detection down to single-digit micromolar concentrations. The platform's adaptability suggests potential for diverse analyte sensing applications.

Publisher

Nature Communications

Published On

Mar 30, 2024

Authors

Mark Ferris, Gary Zabow

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