logo
ResearchBunny Logo
Organic electrochemical neurons and synapses with ion mediated spiking

Engineering and Technology

Organic electrochemical neurons and synapses with ion mediated spiking

P. C. Harikesh, C. Yang, et al.

Discover the groundbreaking potential of organic electrochemical neurons (OECNs) that seamlessly integrate with a Venus Flytrap, showcasing bio-compatible spiking and plasticity. This revolutionary research, conducted by Padinhare Chalakkal Harikesh and colleagues, explores the future of artificial neuronal systems that can interact with various biological signaling systems.

00:00
00:00
Playback language: English
Abstract
Traditional silicon-based neuromorphic devices have limitations in bio-integration due to poor biocompatibility, circuit complexity, and operational principles different from biological ion signal modulation. This paper introduces the first organic electrochemical neurons (OECNs) with ion-modulated spiking, based on all-printed complementary organic electrochemical transistors. These OECNs, successfully bio-integrated with a Venus Flytrap, induce lobe closure upon stimulation. Integration with all-printed organic electrochemical synapses (OECSs) demonstrates short-term plasticity (paired-pulse facilitation) and long-term plasticity (retention >1000 s), enabling Hebbian learning. Operating below 0.6 V and responding to multiple stimuli, these soft, flexible OECNs offer potential for localized artificial neuronal systems integrable with plant, invertebrate, and vertebrate bio-signaling systems.
Publisher
Nature Communications
Published On
Feb 22, 2022
Authors
Padinhare Chalakkal Harikesh, Chi-Yuan Yang, Deyu Tu, Jennifer Y. Gerasimov, Abdul Manan Dar, Adam Armada-Moreira, Matteo Massetti, Renee Kroon, David Bliman, Roger Olsson, Eleni Stavrinidou, Magnus Berggren, Simone Fabiano
Tags
organic electrochemical neurons
biocompatibility
spiking
plasticity
Hebbian learning
biological systems
bio-integration
Listen, Learn & Level Up
Over 10,000 hours of research content in 25+ fields, available in 12+ languages.
No more digging through PDFs, just hit play and absorb the world's latest research in your language, on your time.
listen to research audio papers with researchbunny