This study investigates the effectiveness of One Health collaborations versus single-sector actions in mitigating SARS-CoV-2 transmission among and between captive and wild white-tailed deer. A multisector effort, involving wildlife management, agricultural management, and public health agencies, framed the problem, developed a dynamic model linking deer harvest and SARS-CoV-2 spread, and evaluated management alternatives. Results showed that while single-sector actions reduced transmission, the most effective approach required collaborative actions across all three sectors. The study quantitatively supports the superiority of One Health actions but highlights the importance of coordination for managing this evolving system.

Jonathan D. Cook, Elias Rosenblatt, Graziella V. Direnzo, Evan H. Campbell Grant, Brittany A. Mosher, Fernando Arc, Sonja A. Christensen, Ria R. Ghai, Michael C. Runge