This paper presents a sensitive indirect fluorescent sensing mechanism (IFSM) for detecting non-fluorescent microcystin (MC-RR), using molecular imprinting technology and charge transfer effects. A molecular imprinted thin film is immobilized on zinc ferrite nanoparticles, utilizing arginine as a dummy template. Implemented on a paper-based microfluidic chip, this platform enables quantitative MC-RR assay at trace levels (LOD 0.43 µg/L, 20 min analysis time) in real water samples without pretreatment. The IFSM is adaptable to various non-fluorescent species.
Publisher
Nature Communications
Published On
Oct 17, 2023
Authors
Bowei Li, Ji Qi, Feng Liu, Rongfang Zhao, Maryam Arabi, Abbas Ostovan, Jinming Song, Xiaoyan Wang, Zhiyang Zhang, Lingxin Chen
Tags
fluorescent sensing
molecular imprinting
microcystin detection
paper-based microfluidic chip
environmental monitoring
zinc ferrite nanoparticles
trace levels
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