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Learning interpretable dynamics of stochastic complex systems from experimental data

Biology

Learning interpretable dynamics of stochastic complex systems from experimental data

T. Gao, B. Barzel, et al.

Discover how the Langevin Graph Network Approach (LaGNA) revolutionizes the inference of stochastic differential equations from empirical data for complex networks. Developed by Ting-Ting Gao, Baruch Barzel, and Gang Yan, this innovative method outshines existing techniques, providing critical insights into bird flock dynamics and tau pathology in mice.

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Playback language: English
Abstract
Inferring stochastic differential equations (SDEs) from empirical data for complex networked systems remains challenging. This paper introduces the Langevin Graph Network Approach (LaGNA), which outperforms five state-of-the-art methods in learning hidden SDEs. Applications to bird flock movement and tau pathology diffusion in mouse brains demonstrate LaGNA's ability to infer governing equations, providing insights into flocking dynamics and tau spread, enabling early prediction of tau occupation and revealing distinct pathology dynamics in mutant mice.
Publisher
Nature Communications
Published On
Jul 17, 2024
Authors
Ting-Ting Gao, Baruch Barzel, Gang Yan
Tags
Stochastic Differential Equations
Langevin Graph Network Approach
Complex Networks
Flocking Dynamics
Tau Pathology
Data Inference
Mouse Brains
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