This paper presents the development of a stand-alone, conformable, fully organic bioelectronic device—the vertical internal ion-gated organic electrochemical transistor (vIGT)—capable of signal acquisition, processing, and wireless communication. The vIGT architecture incorporates a vertical channel and a miniaturized hydration access conduit, enabling megahertz-signal-range operation within densely packed arrays without crosstalk. Implanted in rodents, the device successfully acquired and transmitted neurophysiologic brain signals, showcasing potential for diverse clinical applications.

Claudia Cea, Zifang Zhao, Duncan J. Wisniewski, George D. Spyropoulos, Anastasios Polyravas, Jennifer N. Gelinas, Dion Khodagholy