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Abstract
This research paper introduces an injectable hydrogel electrode designed to address ventricular arrhythmias, a leading cause of sudden cardiac death. The hydrogel, delivered via catheter, fills coronary veins, creating flexible electrodes reaching the mid-myocardium. In a pig model, the electrode successfully paced the heart, exhibiting QRS morphology similar to native sinus rhythm. Electroanatomical mapping showed faster activation than conventional pacing, suggesting potential for eliminating lethal arrhythmias and enabling painless defibrillation.
Publisher
Nature Communications
Published On
Jan 02, 2024
Authors
Gabriel J. Rodriguez-Rivera, Allison Post, Mathews John, Skylar Buchan, Drew Bernard, Mehdi Razavi, Elizabeth Cosgriff-Hernandez
Tags
injectable hydrogel
ventricular arrhythmias
cardiac death
flexible electrodes
pacing
defibrillation
myocardium

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