Medicine and Health

Gut microbiota and metabolic health among overweight and obese individuals

M. Kim, K. E. Yun, et al.

Discover how gut microbiota composition varies with metabolic health in obese individuals. This groundbreaking research by Mi-Hyun Kim and colleagues reveals that metabolically unhealthy individuals possess less diverse gut microbiota, highlighting the potential of microbiome modulation in preventing metabolic disorders.

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Abstract

This study investigated the composition of gut microbiota according to metabolic health status in obese and overweight subjects. 747 overweight or obese adults were categorized by metabolic health status, and their fecal microbiota were profiled using 16S ribosomal RNA gene sequencing. The metabolically unhealthy (MU) group showed lower gut microbiota diversity than the metabolically healthy (MH) group. *Oscillospira* and Coriobacteriaceae were associated with good metabolic health in overweight and obese populations. Modulation of the gut microbiome may help prevent metabolic abnormalities in obese individuals.

Publisher

Scientific Reports

Published On

Nov 10, 2020

Authors

Mi-Hyun Kim, Kyung Eun Yun, Jimin Kim, Eunkyo Park, Yoosoo Chang, Seungho Ryu, Hyung-Lae Kim, Han-Na Kim

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