Medicine and Health

Effectiveness of pre-pregnancy lifestyle in preventing gestational diabetes mellitus—a systematic review and meta-analysis of 257,876 pregnancies

S. Sampathkumar, D. Parkhi, et al.

This systematic review and meta-analysis by Swetha Sampathkumar, Durga Parkhi, Yonas Ghebremichael-Weldeselassie, Nithya Sukumar, and Ponnusamy Saravanan reveals insights into how pre-pregnancy lifestyle choices can impact the risk of gestational diabetes mellitus (GDM). With data from 30 studies involving over 257,000 pregnancies, the findings encourage ongoing research in this vital health area.

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Abstract

This systematic review and meta-analysis investigated the effectiveness of pre-pregnancy lifestyle in preventing gestational diabetes mellitus (GDM). 30 studies (257,876 pregnancies) were included. Meta-analysis of randomized controlled trials (RCTs) showed a non-significant reduction in GDM risk (OR 0.76, 95% CI: 0.50–1.17, p = 0.21). However, meta-analysis of cohort studies revealed that pre-pregnancy physical activity, low carbohydrate/low sugar diets, and higher quality diet scores were associated with a reduced GDM risk (ORs ranging from 0.71 to 0.72). The limited number of RCTs, especially from low- and middle-income countries, highlights the need for further research.

Publisher

Nutrition and Diabetes

Published On

Nov 16, 2023

Authors

Swetha Sampathkumar, Durga Parkhi, Yonas Ghebremichael-Weldeselassie, Nithya Sukumar, Ponnusamy Saravanan

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