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Abstract
High-throughput, high-accuracy detection of emerging viruses is crucial for controlling outbreaks. This paper presents a novel method for detecting coronaviruses using nanopores and artificial intelligence, eliminating the need for RNA extraction. The platform, termed the artificially intelligent nanopore, accurately identified four coronaviruses (HCoV-229E, SARS-CoV, MERS-CoV, and SARS-CoV-2) in saliva samples with 90% sensitivity and 96% specificity within 5 minutes.
Publisher
Nature Communications
Published On
Jun 17, 2021
Authors
Masateru Taniguchi, Shohei Minami, Chikako Ono, Rina Hamajima, Ayumi Morimura, Shigeto Hamaguchi, Yukihiro Akeda, Yuta Kanai, Takeshi Kobayashi, Wataru Kamitani, Yutaka Terada, Koichiro Suzuki, Nobuaki Hatori, Yoshiaki Yamagishi, Nobuei Washizu, Hiroyasu Takei, Osamu Sakamoto, Norihiko Naono, Kenji Tatematsu, Takashi Washio, Yoshiharu Matsuura, Kazunori Tomono
Tags
coronaviruses
detection
nanopores
artificial intelligence
sensitivity
specificity
saliva samples

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