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Boron-assisted abiotic polypeptide synthesis

Chemistry

Boron-assisted abiotic polypeptide synthesis

Y. Sumie, K. Sato, et al.

This groundbreaking study by Yuki Sumie, Keiichiro Sato, Takeshi Kakegawa, and Yoshihiro Furukawa reveals that boric acid facilitates amino acid polymerization in acidic and near-neutral conditions, paving the way for RNA formation and essential protein-RNA interactions—key processes in the origin of life.

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Playback language: English
Abstract
The abiotic synthesis of peptides has been limited in short amino acid length and is favored in highly alkaline conditions where RNAs are unstable. This study demonstrates that boric acid enables amino acid polymerization at acidic and near-neutral pH levels through simple heating experiments. This boron-assisted polypeptide synthesis occurs in prebiotically plausible environments, potentially allowing for simultaneous RNA formation and protein-RNA interactions, crucial steps in the origin of life.
Publisher
Communications Chemistry
Published On
May 11, 2023
Authors
Yuki Sumie, Keiichiro Sato, Takeshi Kakegawa, Yoshihiro Furukawa
Tags
abiotic synthesis
peptides
amino acids
boric acid
RNA formation
origin of life

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