Medicine and Health

Associations of body composition and physical fitness with gestational diabetes and cardiovascular health in pregnancy: Results from the HealthyMoms trial

P. Henriksson, J. Sandborg, et al.

Explore groundbreaking insights from the HealthyMoms trial, revealing how body composition and physical fitness in early pregnancy significantly influence gestational diabetes and cardiovascular health. This research, conducted by Pontus Henriksson, Johanna Sandborg, Emmie Söderström, Marja H. Leppänen, Victoria Snekkenes, Marie Blomberg, Francisco B. Ortega, and Marie Löf, emphasizes the critical role of excess fat mass in maternal health.

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Abstract

This cross-sectional study (n=303) from the HealthyMoms trial examined associations of body composition (fat mass index, % fat mass, fat-free mass index, BMI) and physical fitness (cardiorespiratory fitness, handgrip strength) with gestational diabetes and cardiovascular health in early pregnancy. Fat mass index, % fat mass, and BMI were strongly associated with gestational diabetes, HOMA-IR, blood pressure, and MetS score. Fat-free mass index showed weaker associations, attenuated after adjusting for fat mass index. Greater cardiorespiratory fitness was linked to lower HOMA-IR and MetS score, but this was attenuated after adjusting for fat mass index. The study concludes that excess fat mass, not fat-free mass, is the primary focus for clinical care regarding gestational diabetes and cardiovascular health.

Publisher

Nutrition and Diabetes

Published On

Jun 07, 2021

Authors

Pontus Henriksson, Johanna Sandborg, Emmie Söderström, Marja H. Leppänen, Victoria Snekkenes, Marie Blomberg, Francisco B. Ortega, Marie Löf

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