logo
ResearchBunny Logo
A rare gain of function mutation in a wheat tandem kinase confers resistance to powdery mildew

Agriculture

A rare gain of function mutation in a wheat tandem kinase confers resistance to powdery mildew

P. Lu, L. Guo, et al.

Discover how a rare genetic mutation in a tandem kinase protein is paving the way for powdery mildew resistance in wheat. This groundbreaking research, conducted by a team of experts, reveals the vital role of the *Pm24* gene derived from the Chinese landrace Hulutou. Uncover the future of wheat disease resistance through this significant advancement in plant genetics.

00:00
00:00
Playback language: English
Abstract
Powdery mildew, caused by *Blumeria graminis* f. sp. *tritici* (Bgt), is a devastating wheat disease. This study reports the map-based cloning of the powdery mildew resistance gene *Pm24* from the Chinese wheat landrace Hulutou. *Pm24* encodes a tandem kinase protein (WTK3) with kinase-pseudokinase domains. A rare 6-bp deletion, resulting in a two-amino acid deletion (lysine-glycine) in the kinase I domain, is crucial for resistance. Transgenic assays and mutant analyses confirmed WTK3's role and the specificity of the two-amino-acid deletion in conferring resistance.
Publisher
Nature Communications
Published On
Feb 03, 2020
Authors
Ping Lu, Li Guo, Zhenzhong Wang, Beibei Li, Jing Li, Yahui Li, Dan Qiu, Wenqi Shi, Lijun Yang, Ning Wang, Guanghao Guo, Jingzhong Xie, Qiuhong Wu, Yongxing Chen, Miaomiao Li, Huaizhi Zhang, Lingli Dong, Panpan Zhang, Keyu Zhu, Dazhao Yu, Yan Zhang, Karin R. Deal, Naxin Huo, Cuimin Liu, Ming-Cheng Luo, Jan Dvorak, Yong Qiang Gu, Hongjie Li, Zhiyong Liu
Tags
powdery mildew
Pm24 gene
wheat resistance
kinase protein
genetic mutation
transgenic assays
plant genetics
Listen, Learn & Level Up
Over 10,000 hours of research content in 25+ fields, available in 12+ languages.
No more digging through PDFs, just hit play and absorb the world's latest research in your language, on your time.
listen to research audio papers with researchbunny