This paper reports the growth of engineered living materials (ELMs) from *Caulobacter crescentus* cells displaying and secreting a self-interacting protein. This protein formed a de novo matrix, assembling cells into centimeter-scale ELMs. The authors discovered design and assembly rules allowing them to tune the ELMs' composition, mechanical properties, and functionality, providing a foundation for robustly engineering ELMs with desirable macroscopic functions.
Publisher
Nature Communications
Published On
Sep 21, 2022
Authors
Sara Molinari, Robert F. Tesoriero Jr., Dong Li, Swetha Sridhar, Rong Cai, Jayasree Soman, Kathleen R. Ryan, Paul D. Ashby, Caroline M. Ajo-Franklin
Tags
engineered living materials
Caulobacter crescentus
self-interacting protein
centimeter-scale
mechanical properties
composition
macroscopic functions
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