Medicine and Health

4D polycarbonates via stereolithography as scaffolds for soft tissue repair

A. C. Weems, M. C. Arno, et al.

Explore the cutting-edge research by Andrew C. Weems, Maria C. Arno, Wei Yu, Robert T. R. Huckstepp, and Andrew P. Dove on innovative soft tissue repair using 3D-printed scaffolds made from elastomeric polycarbonates. These scaffolds not only conform to tissue voids but also show promising results in enhancing adipose tissue engineering through significant in vivo benefits.

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Abstract

This paper presents the design and in vivo testing of soft, elastomeric aliphatic polycarbonate-based materials for use as 3D-printed scaffolds in soft tissue repair. The scaffolds exhibit shape memory properties, allowing them to conform to tissue voids. In vivo studies showed adipocyte infiltration and neovascularization, with reduced collagen capsule thickness, indicating high promise for adipose tissue engineering.

Publisher

Nature Communications

Published On

Jul 15, 2021

Authors

Andrew C. Weems, Maria C. Arno, Wei Yu, Robert T. R. Huckstepp, Andrew P. Dove

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